1.Kirish
Vinkristin sulfat - antimitotik va antineoplastik ta'sirga ega Catharanthus roseus (Vinca rosea L.) o'simlikidan ajratilgan tabiiy alkaloidning sulfat tuzi. Vinkristin hujayra siklining S fazasida mikronaychalar va shpindel oqsillari bilan qaytarib bo'lmaydigan tarzda bog'lanadi va mitotik shpindelning shakllanishiga to'sqinlik qiladi va shu bilan o'simta hujayralarini metafazada ushlab turadi. Ushbu agent shuningdek, mikrotubullarni depolimerizatsiya qiladi va shuningdek, aminokislota, siklik AMP va glutation metabolizmiga aralashishi mumkin; kalmodulinga bog'liq- Ca(2 plyus )-faollashgan ATPaz faolligi; hujayrali nafas olish; va nuklein kislota va lipidlar biosintezi.
2.Asosiy funktsiya
Vinkristin sulfat kukuni 2068-78-2 turli xil o'tkir leykemiyalarni, ayniqsa o'tkir limfoblastik leykemiyani davolashda yaxshi ta'sir ko'rsatadi. Bundan tashqari, u malign limfoma, xorioepitelioma, ko'krak karsinomasi, neyroblastoma, nefroblastomalun, miya saratoni, miya saratoni uchun ba'zi ta'sir ko'rsatadi. leyomyosarkoma, bachadon bo'yni saratoni va ovqat hazm qilish yo'llarining shishi.
3. Ilova
Vincristine Sulfate Powder 2068-78-2 can influence the formation of spindle cells, mitosis stops in the middle of the cell cycle M phase there is delay or block action. In addition, also inhibit the synthesis of purine, RNA and DNA. This drug belongs to a cell cycle specific drugs. The main clinical for the treatment of acute lymphoblastic leukemia, Hodgkin's disease, malignant lymphoma, small cell lung cancer, breast cancer, ovarian cancer, gastrointestinal cancer.
4.Sifat standarti
TAHLIL | XUSUSIYAT |
Tahlil (HPLC) | 99 foiz -101 foiz |
Belgilar / tashqi ko'rinish | Oqdan oq ranggacha kukun |
Xushbo'y hid va ta'm | Hidsiz |
Identifikatsiya | Ijobiy reaktsiya |
Mesh hajmi/elak tahlili | 100 foiz 80 meshdan o'tadi |
Eruvchanlik | Xloroformda oson eriydi |
Quritishda yo'qotish | 1 foiz Maks |
Suv | 2.0 foizdan kam yoki unga teng |
Erish nuqtasi | 211-216 daraja |
Yonayotganda qoldiq | 0.1 foiz Maks |
Maxsus aylanish (HCCl3) | ortiqcha 41 daraja va 44 daraja |
PH | 5.0-7.0 |
Metanol | 0.30 foizdan kam yoki unga teng |
Og'ir metallar | NMT 10ppm |
Mikrobiologik nazorat Jami plastinka soni zamburug'lar Salmonella Coli | <1000 cfu/g=""> <100 negative=""> |
5.Tahlil usuli
6.NMR
7. Barqarorlik va xavfsizlik
Barqarorlik:
Tegishli sharoitlarda (xona harorati) barqaror. Barqarorlik ma'lumotlar varag'i sizning so'rovingiz bo'yicha mavjud.
Xavfsizlik:
AQShning GARS (Umumiy ravishda xavfsiz deb e'tirof etilgan) bayonotiga ko'ra, u inson iste'moli uchun xavfsizdir.
8. Oqim sxemasi
9. Mijoz sharhlari
Bizda Alibaba, Chemicalbook va LookChem do'konlari bor, yuqori sifatli mahsulotlar va shartsiz xizmatlar orqali biz juda ko'p ijobiy sharhlarga ega bo'ldik.
10. Bizning sertifikatlarimiz
Over the years, we have been committed to the product manufacture optimization and quality system establishment. We've set up the quality management system and obtained certificates of it.
11. Bizning mijozlarimiz
We've established business relationship with Abbott, Unilever, Shiseido, KANS and SIMM, etc.
12. Ko'rgazmalar
Biz tez-tez CPhI, FIC, API, Vitafoods, SupplesideWest kabi xalqaro ko'rgazmalarda qatnashamiz.
Issiq teglar: vinkristin sulfat kukuni 2068-78-2, ishlab chiqaruvchilar, etkazib beruvchilar, zavod, ulgurji, sotib olish, narx, eng yaxshi, ommaviy, sotuvda
